Leiden University

Universiteit Leiden
Analytical BioSceinces – Leiden Academic Centre for Drug Research
Gorlaeus Laboratories
Bioscience Park
Einsteinweg 55
2333 CC Leiden

The Division of Analytical Biosciences is part of the Leiden Academic Centre for Drug Research (LACDR) at the Faculty of Science of Leiden University. LACDR is a leading institute dedicated to world-class research and education in drug discovery and development. Leiden is the initiator and leader of the Netherlands Metabolomics Centre (NMC), a multidisciplinary public-private partnership between key academic players, clinical centers, research institutes, and industrial partners. Leiden has extensive experience in biomarker discovery with metabolomics in clinical and preclinical studies.

  • Photo of Thomas Hankemeier
    Prof. Dr. Thomas Hankemeier

    Prof. Dr. Thomas Hankemeier is head of the Division for Analytical Biosciences at the Leiden Academic Centre for Drug Research (LACDR) of Leiden University.

    His research is aimed at developing innovative analytical tools for metabolomics-driven systems biology in personalized health strategies.

    As work package leader for WP4, Prof Hankemeier will be responsible for setting-up optimal metabolomic and morphological phenotyping platforms for clinical, in vitro, and in vivo Parkinson’s disease with mitochondrial dysfunction.

  • Photo of Ronan Fleming
    Assist. Prof. Dr. Ronan Fleming

    Coordinator and work package leader for WP5 and WP6.

    Dr. Ronan Fleming is an Assistant Professor at the Leiden Academic Centre for Drug Research (LACDR) of Leiden University. He leads the Systems Biochemistry Group, an interdiscipinary research group of mathematical, computational and experimental biologists.

    He is responsible for the coordination of the scientific developments and overall quality assurance of the project.

  • Photo of Amy Harms
    Dr. Amy Harms

    Dr. Amy Harms is Lab Manager of the Metabolomics Facility at the Leiden Academic Centre for Drug Research (LACDR)

    Please complete this sentence in relation to your work in the project.

    She manages the metabolomics core facility for the Biomedical Metabolomics Facility Leiden. She has more than 25 years of experience in the field of mass spectrometry. She is particularly interested in instrumentation, data processing strategies, and quality control. Her expertise allows her to contribute to the experimental design, the actual collecting of data, evaluation and interpretation of data, and integration into the larger goals of the proposed projects.

    She will be responsible for the metabolomics analysis of clinical samples in WP4.

  • Photo of Agnieszka Wegrzyn
    Agnieszka Wegrzyn

    Dr. Agnieszka Wegrzyn is a PostDoc in at the Leiden Academic Centre for Drug Research (LACDR).

  • Photo of Edinson Lucumi
    Edinson Lucumi

    Edinson Lucumi is a postdoc at the Leiden Academic Centre for Drug Research (LACDR).

    He is an experienced experimental cell biologist. His work in the project will contribute to the metabolomic phenotyping of spent media from iPSC derived neurons cultured in 3D microfluidics.

  • Photo of Diana El Assal
    Diana El Assal

    Diana El Assal is a PhD student at the Leiden Academic Centre for Drug Research (LACDR).

    Using a systems biology approach, Diana is currently reconstructing the biochemical networks of neuronal mitochondria. She has experience in pharmacology, which in combination with constraint-based modelling (WP5) will be used to elucidate the biochemical pathways that become dysfunctional in mitochondrial Parkinson's disease. The aim of the mitochondrial models is to computationally predict potential drug targets, that can then be tested experimentally.

  • Photo of Cornelius Willacey
    Cornelius Willacey

    Cornelius Willacey is a PhD candidate at the Leiden Academic Centre for Drug Research (LACDR).

    He specialises in pharmacy and pharmacology, and will be expanding his knowledge in the study of metabolites related to mitochondrial dysfunction.

    His work in the project will contribute to the optimisation and miniaturisation of the metabolomics phenotyping platform for Parkinson's disease in WP4.

  • Photo of German Predicat
    German Predicat

    German Predicat is a PhD candidate at the Leiden Academic Centre for Drug Research (LACDR).